Read e-book online Apoptosis Methods in Pharmacology and Toxicology: Approaches PDF

By Myrtle A. Davis

ISBN-10: 0896038904

ISBN-13: 9780896038905

Univ. of Maryland, Baltimore. Discusses laser scanning cytometry for the research of apoptosis, tissue-based equipment of quantification for reviews utilizing animal versions, and practical assays and ELISA ideas. DNLM: Apoptosis--physiology.

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Get Apoptosis Methods in Toxicology PDF

This targeted quantity offers a unmarried, beneficial reference resource for ways that definitively establish and properly quantify apoptosis. The booklet starts off with universal equipment applied to realize and quantitate apoptosis, in addition to apoptosis signaling pathways in toxicological and different similar study.

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1999) Fluorescent molecular probes V: a sensitive caspase-3 substrate for fluorometric assays. Bioorg. Med. Chem. Lett. 9(22), 3231–3236. 56. , Packard, B. , Brown, M. , Wu, M. , and Henkart, P. A. (2000) Assessment of caspase activities in intact apoptotic thymocytes using cell-permeable fluorogenic caspase substrates. J. Exp. Med. 191(11), 1819–1828. 57. , and Reed, J. C. (2000) Fluorogenic substrates as detectors of caspase activity during natural killer cell-induced apoptosis. Methods Mol.

And Webb, W. W. (1999) Fluorescence correlation spectroscopy with single-molecule sensitivity on cell and model membranes. Cytometry 36(3), 176–182. 80. , et al. (1999) Imaging protein kinase Calpha activation in cells. Science 283(5410), 2085–2089. 36 Poot et al. 81. Verveer, P. , Wouters, F. , Reynolds, A. , and Bastiaens, P. I. (2000) Quantitative imaging of lateral ErbB1 receptor signal propagation in the plasma membrane. Science 290(5496), 1567–1570. 82. , et al. (1994) Mitochondrial modifications during rat thymocyte apoptosis: a study at the single cell level.

Science 281(5381), 1309–1312. 9. Afanas’ev, V. , Korol, B. , Nelipovich, P. , Pechatnikov, V. , and Umansky, S. R. (1986) Flow cytometry and biochemical analysis of DNA degradation characteristic of two types of cell death. FEBS Lett. 194(2), 347–350. 10. Telford, W. , King, L. , and Fraker, P. J. (1992) Comparative evaluation of several DNA binding dyes in the detection of apoptosis-associated chromatin degradation by flow cytometry. Cytometry 13(2), 137–143. Apoptotic Cell Death 31 11. , and Darzynkiewicz, Z.

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Apoptosis Methods in Pharmacology and Toxicology: Approaches to Measurement and Quantification by Myrtle A. Davis


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